Product Description
Ames MPF 98/100 is a miniaturized, ready to use Ames Test kit in a liquid microplate format according to ISO 11350. It includes all reagents necessary to run 5 samples with strains TA98 and TA100: 5 vials each of semisolid TA98, TA100, plus Booster, Growth -, Exposure -, Reversion Indicator Media, Ampicillin, Positive Controls, lyophilized Post-Mitochondrial Supernatant S9 from Phenobarbital/Naphtoflavone induced rat liver. Not included in the kit are plastic ware and S9 Cofactor solutions. The kits are quality controlled and do not need a separate quality control (phenotypes) like the agar plate Assay in petri dishes when used as an inhouse test.
Product Documents & Features
Ames mutagenicity assays are important in research applications for:
- the safety of cosmetics and pharmaceuticals
- the exclusion of genotoxic activity in chemicals or pesticides
- the exclusion of mutagenicity in medical devices
- the exclusion of micro-pollutants in drinking water
- the control of absence of genotoxic compounds in surface or waste water, air, soil or sediments
- the research in the field of food ingredients, food packaging
- Quality controlled products: strains, rat liver S9, positive controls, ampicillin and media
- Certificate of Analysis: Provided with the kit
- In accordance with ISO 11350
- Excel Calculation Sheet to support Data Interpretation: Free of charge
- Comparison with agar plate test: Corresponds to 2 x 240 petri dishes.
- Enough Material to process strains individually
- Shipped at room temperature from external storage in Germany or from stock in Switzerland
- High sensitivity (LoD)
- Excellent correlation with agar plate test (see database and publications on this homepage)
- Less hands-on-time and simultaneous processing of several replicates
- Automation available - High throughput format
- 3Rs - 12 fold less consumption of rat liver S9, less test animals
- Less error prone due to easy colorimetric read-out
- Waste - Significant less plastic waste and thus reduced contaminated waste in environment
- 5 Sample Kit when tested in 2 tester strains TA98 and TA100, +/- S9, 3 Replicates, 6 Doses, Positive & Negative Controls: Strains, Media, Ampicillin, Booster, PB-NF induced rat liver S9, Controls and Excel calculation sheet. S9 Cofactor solutions and plastic ware are not included in the kit.
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