5-Diagnostics
5-TEST USP-UFH Anti-Xa starter set
This product is not available for purchase in North America or Nordic and Baltic Countries. Complete set of individual reagents for the measurement of heparin and heparin-like anticoagulants in aqueous solutions using an anti-FXa chromogenic assay for pharmaceutical preparations in compliance with US Pharmacopoeia.
5-TEST USP-UFH Anti-Xa starter set
This product is not available for purchase in North America or Nordic and Baltic Countries. Complete set of individual reagents for the measurement of heparin and heparin-like anticoagulants in aqueous solutions using an anti-FXa chromogenic assay for pharmaceutical preparations in compliance with US Pharmacopoeia.
5-TEST USP-UFH Anti-IIa starter set
This product is not available for purchase in North America or Nordic and Baltic Countries. Complete set of individual reagents for the measurement of heparin in buffer using an anti-FIIa chromogenic assay for pharmaceutical preparations in compliance with US Pharmacopoeia.
5-TEST USP-UFH Anti-IIa starter set
This product is not available for purchase in North America or Nordic and Baltic Countries. Complete set of individual reagents for the measurement of heparin in buffer using an anti-FIIa chromogenic assay for pharmaceutical preparations in compliance with US Pharmacopoeia.
5-TEST USP-LMWH Anti-Xa starter set
This product is not available for purchase in North America or Nordic and Baltic Countries. Complete set of individual reagents for the measurement of heparin and heparin-like anticoagulants in aqueous solutions using an anti-FXa chromogenic assay for pharmaceutical preparations in compliance with US Pharmacopoeia.
5-TEST USP-LMWH Anti-IIa starter set
This product is not available for purchase in North America or Nordic and Baltic Countries. Complete set of individual reagents for the measurement of heparin and heparin-like anticoagulants in buffer using an anti-FIIa chromogenic assay for pharmaceutical preparations in compliance with US Pharmacopoeia.
5-TEST EP-UFH Anti-Xa starter set
This product is not available for purchase in North America or Nordic and Baltic Countries. Complete set of individual reagents for the measurement of heparin in aqueous solutions using an anti-FXa chromogenic assay for pharmaceutical preparations in compliance with European Pharmacopoeia.
5-TEST EP-UFH Anti-IIa starter set
This product is not available for purchase in North America or Nordic and Baltic Countries. Complete set of individual reagents for the measurement of heparin in buffer using an anti-FIIa chromogenic assay for pharmaceutical preparations in compliance with European Pharmacopoeia.
5-TEST EP-LMWH Anti-Xa starter set
This product is not available for purchase in North America or Nordic and Baltic Countries. Complete set of individual reagents for the measurement of heparin in aqueous solutions using an anti-FXa chromogenic assay for pharmaceutical preparations in compliance with European Pharmacopoeia.
5-TEST EP-LMWH Anti-IIa starter set
This product is not available for purchase in North America or Nordic and Baltic Countries. Complete set of individual reagents for the measurement of heparin and heparin-like anticoagulants in buffer using an anti-FIIa chromogenic assay for pharmaceutical preparations in compliance with European Pharmacopoeia.
DP-Filter®
For Research Use Only. The DP Filter is a device for the filtration of citrated plasmas to remove Direct Oral Anticoagulants (DOAC) including dabigatran, edoxaban, apixaban and rivaroxaban at concentrations from 0,000 to 1,000 ng/mL.
5D Protein Stabilizer (50 mL)
For In Vitro Use Only. For Research Use Only. Not for use in diagnostic procedures. Hydrolyzed porcine collagen peptide fraction, from dermal origin, which can be used as a protein stabilizer for lyophilized or liquid formulations or as a blocking agent for coated surfaces.
5D Protein Stabilizer (1000 mL)
For In Vitro Use Only. For Research Use Only. Not for use in diagnostic procedures. Hydrolyzed porcine collagen peptide fraction, from dermal origin, which can be used as a protein stabilizer for lyophilized or liquid formulations or as a blocking agent for coated surfaces.
5D Protein Stabilizer (100 mL)
For In Vitro Use Only. For Research Use Only. Not for use in diagnostic procedures. Hydrolyzed porcine collagen peptide fraction, from dermal origin, which can be used as a protein stabilizer for lyophilized or liquid formulations or as a blocking agent for coated surfaces.
DOAC-REMOVE 250
For In Vitro Use Only. For Research Use Only. Not for Use in Diagnostic Procedures. For the removal of Direct Oral Anticoagulants (DOACs) in Human Citrated Plasma.
DOAC-REMOVE 50
For In Vitro Use Only. For Research Use Only. Not for Use in Diagnostic Procedures. For the removal of Direct Oral Anticoagulants (DOACs) in Human Citrated Plasma.
DOAC-REMOVE 20
For In Vitro Use Only. For Research Use Only. Not for Use in Diagnostic Procedures. For the removal of Direct Oral Anticoagulants (DOACs) in Human Citrated Plasma.
5-BUFFER USP/Ph.Eur. Tris-NaCl-EDTA-PEG-6000 Buffer salts pH 8.4
This product is not available for purchase in North America or Nordic and Baltic Countries. 5-BUFFER USP/Ph.Eur. Tris-NaCI-EDTA-PEG-6000 Buffer salts, pH 8.4 for the quality control of the anti-FXa and anti-FIIa activity of UFH in compliance with European Pharmacopoeia or with US Pharmacopoeia.
5-BUFFER USP/Ph.Eur. Tris-NaCl-BSA Buffer salts pH 7.4
This product is not available for purchase in North America or Nordic and Baltic Countries. 5-BUFFER USP/Ph.Eur. Tris-NaCI-BSA Buffer salts, pH 7.4 for the quality control of the anti-FXa and anti-FIIa activity of LMWH in compliance with European Pharmacopoeia.
5-BUFFER USP Tris-NaCl-PEG-6000 Buffer salts pH 7.4
This product is not available for purchase in North America or Nordic and Baltic Countries. 5-BUFFER USP Tris-NaCI-PEG-6000 Buffer salts, pH 7.4 for the quality control of the anti-FXa and anti-FIIa activity of LMWH in compliance with US Pharmacopoeia.
5-BUFFER USP/Ph.Eur. Tris-NaCl-EDTA Buffer salts pH 8.4
This product is not available for purchase in North America or Nordic and Baltic Countries. 5-BUFFER USP/Ph.Eur. Tris-NaCI-EDTA Buffer salts, pH 8.4 for the quality control of anti-FXa and anti-FIIa activity of LMWH in compliance with European Pharmacopoeia or with US Pharmacopoeia.
5-BUFFER USP Tris-NaCl Buffer salts pH 7.4
This product is not available for purchase in North America or Nordic and Baltic Countries. 5-BUFFER USP Tris-NaCI Buffer salts, pH 7.4 for the quality control of the anti-FXa and anti-FIIa activity of LMWH in compliance with US Pharmacopoeia.
HEPA-Remove
HEPA-Remove is for In Vitro use only. For Research Use Only. Not for Use in Diagnostic Procedures. HEPA-Remove, 1 mg, Lyophilized powder is a syntheitc peptide designed to inhibit heparin and heparin-like activity.
5-ENZYME Convulxin
For in vitro use only. For Research Use Only. Not for use in Diagnostic Procedures. Convulxin, from Crotalus durissus terrificus venom, is a protein which activates blood platelets via binding and clustering of GPVI-receptors
under physiological conditions.
Aprotinin
For Research Use Only. Not for use in diagnostic procedures. For in vitro use only. Aprotinin is a multiple inhibitor of many serine proteases, including Trypsin, Plasmin, Urokinase, Kallicrein, Factor XIIa, etc. Aprotinin forms stable complexes with these enzymes.
5-ENZYME Thrombin (Human)
This product is not available for purchase in North America and Nordic and Baltic Countries. Prepared from a prothrombin complex concentrate extracted from human citrated plasma and fully activated in a purified system. Thrombin is then purified using an ion exchange chromatography and stabilised. It is a highly purified preparation, mainly in the form, with a specific activity ≥ 1500 NIH/mg.
5-ENZYME Factor Xa (Bovine)
This product is not available for purchase in North America and Nordic and Baltic Countries. Highly purified Factor X from citrated bovine plasma, activated with agarose bound RVV.
5-PROTEIN Antithrombin (Human)
This product is not available for purchase in North America and Nordic and Baltic Countries. Highly purified from human plasma using a combination of affinity and ion-exchange chromatographies.
5-ELISA ANNEXIN A1 Antigen
This sandwich ELISA is designed with polyclonal antibodies coated onto the plate for capturing ANNEXIN A1 (ANXA1) in the tested sample. Following a washing step, captured ANXA1 is tagged with a peroxidase-labelled polyclonal antibody, which binds onto the free epitopes in a dose-dependent manner. After washing away the excess of immunoconjugate, the substrate, 3,3′,5,5′ Tetramethylbenzidine (TMB) with hydrogen peroxide (H2O2) is introduced and a blue color develops, which turns yellow when the reaction is stopped with sulfuric acid. This color is measured at 450nm, and the measured value is directly proportional to the amount of ANXA1 present in the tested sample. Results are expressed in ng/ml, by reference to a calibrated internal reference preparation of human recombinant ANXA1. ANXA1, or Lipocortin I, is a 37 kDa protein from the annexin family with strong anti-inflammatory and pro-resolving activities (Perretti and D’Aquisto, Nat Rev Immunol 2009). ANXA1 is highly expressed in neutrophils, monocytes and macrophages and modestly in mast cells, endothelial cells, epithelial cells and fibroblasts.The 5-ELISA Annexin A1 Antigen kit is a two-site enzyme immunoassay for measuring Annexin A1 antigen in plasma or in any biological fluid where it must be tested.
5-ELISA ACE 2 Antigen
This sandwich ELISA is designed with polyclonal antibodies coated onto the plate for capturing soluble forms of Angiotensin Converting Enzyme 2 (ACE2) in the tested sample. Following a washing step, captured ACE2 is tagged with aperoxidase-labelled polyclonal antibody, which binds onto its free epitopes in a dose-dependent manner. After washing away the excess of immunoconjugate, the substrate, 3,3′,5,5′ Tetramethylbenzidine (TMB) with hydrogen peroxide (H2O2) is introduced and a blue color develops, which turns yellow when the reaction is stopped with sulfuric acid. This color is measured at 450 nm, and is directly proportional to the amount of ACE2 present in the tested sample. Results are expressed in ng/ml, by reference to a plasma calibrator, supplemented with recombinant ACE2, and established against an internal reference preparation. ACE2, is a cell surface receptor, present on many cell types. It lowers blood pressure by converting angiotensin II (a vasoconstrictor) to angiotensin 1-7, a vasodilator. It is a major player of the Renin-Angiotensin-Aldosterone System (RAAS). ACE2 is also present in the soluble form in blood circulation, as the result of its extracellular domain cleavage by ADAM 17, releasing it from cell surface. The soluble form is essential for cleaving angiotensin II and lowering blood pressure. Increased concentrations of soluble ACE2 can be associated to various cardiovascular diseases.
